Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12629250 | 1.00 | CTSK (0.40) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL13623345 | 1.00 | CTSK (0.40) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL4294234 | 1.00 | CTSK (0.40) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL12410348 | 0.99 | CTSK (0.41) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL12410343 | 0.95 | CTSK (0.42) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL12676608 | 0.95 | CTSK (0.42) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL1127882 | 0.95 | CTSK (0.42) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL12629356 | 0.88 | CTSK (0.50) | CTSKCTSSBIRC2 | |
| SCHEMBL1117254 | 0.87 | CTSK (0.40) | CTSKHDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL1117169 | 0.87 | CTSK (0.40) | CTSKHDAC4HDAC1HDAC6ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130149243-A1 | METHOD FOR PRODUCTION OF F-18 LABELED GLUTAMIC ACID DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-13 | — | — | US | disclosed |
| US-20110104057-A1 | Novel [F-18]-labelled L-glutamic acid and L-glutamine derivatives (II), their use and processes for their preparation | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130149243-A1 | METHOD FOR PRODUCTION OF F-18 LABELED GLUTAMIC ACID DERIVATIVES | GLUL, SLC18A2, SLC1A2 | CTSK 3026/4885HDAC4 4361/4885HDAC1 4604/4885 |
| US-20110104057-A1 | Novel [F-18]-labelled L-glutamic acid and L-glutamine derivatives (II), their use and processes for their preparation | GLUL, QPCT, SLC1A2 | CTSK 2544/4885HDAC4 4495/4885HDAC1 4499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.