Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29212519 | 1.00 | CA2 (0.46) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL20954187 | 1.00 | — | — | |
| Phosphoric Acid SCHEMBL716509 | 1.00 | — | — | |
| Phosphoric Acid SCHEMBL11076118 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL37101 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL9491961 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL1037991 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL8087868 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL11781339 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL29008977 | 0.94 | CA2 (0.42) | CA2SLC34A1KDM4EMMP2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110527330-A | A kind of waterproof material formula and preparation method | GUANGZHOU YUSHEN ARCHITECTURAL WATERPROOF ENG CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-110339394-A | A kind of material preparing bone defect repair support and preparation method | 陶合体科技(苏州)有限责任公司 | 2019-10-18 | — | — | CN | claimed |
| CN-110282998-A | Calcium phosphate porous ceramics and preparation method thereof based on calcium sulfate salt cladding | 陶合体科技(苏州)有限责任公司 | 2019-09-27 | — | — | CN | claimed |
| CN-110251723-A | A kind of porous composite ceramics and preparation method thereof being able to guide osteanagenesis | 陶合体科技(苏州)有限责任公司 | 2019-09-20 | — | — | CN | claimed |
| US-8067069-B2 | Incubation substrate with Group 2a compound and phosphoric acid; medical equipment; prosthetics | DEPUY PRODUCTS, INC. (US) | 2011-11-29 | — | — | US | claimed |
| CN-110527330-A | A kind of waterproof material formula and preparation method | GUANGZHOU YUSHEN ARCHITECTURAL WATERPROOF ENG CO LTD | 2019-12-03 | — | — | CN | disclosed |
| CN-110251723-A | A kind of porous composite ceramics and preparation method thereof being able to guide osteanagenesis | 陶合体科技(苏州)有限责任公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-107073142-A | For radiophotography and the strontium phosphate particulate of therapy | MO-SCI 公司 | 2017-08-18 | — | — | CN | disclosed |