Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31570073 | 0.90 | KMT2A (0.54) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9797043 | 0.90 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL5189053 | 0.87 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL30040195 | 0.87 | CYP2C19 (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29543730 | 0.87 | KMT2A (0.70) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3358264 | 0.87 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL111479 | 0.87 | KMT2A (0.70) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL637658 | 0.87 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6421670 | 0.87 | CYP2C19 (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL17429386 | 0.87 | POLB (0.54) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280106-A1 | Pituitary adenylate cyclase acivating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use | ADCYAP1R1, VIPR2, ADCY2 | ALDH1A1 2368/4885NPC1 2197/4885RAB9A 2110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.