Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.45 |
| ▸ | F10 | P00742 | 10/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791131 | 0.84 | CA2 (0.46) | CA2F10 | |
| SCHEMBL4625640 | 0.82 | CA2 (0.47) | CA2F10 | |
| SCHEMBL12157405 | 0.76 | CA2 (0.67) | CA2 | |
| SCHEMBL12278575 | 0.74 | CA2 (0.40) | CA2 | |
| SCHEMBL12277798 | 0.74 | CA2 (0.40) | CA2 | |
| SCHEMBL27526728 | 0.73 | CA2 (0.38) | CA2F10 | |
| SCHEMBL7012928 | 0.72 | CA2 (0.43) | CA2F10 | |
| SCHEMBL6726277 | 0.71 | USP2 (0.56) | F10 | |
| SCHEMBL6730061 | 0.71 | F10 (0.54) | F10 | |
| SCHEMBL144486 | 0.71 | ALDH1A1 (0.38) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |