Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638163 | 0.90 | ZDHHC7 (0.43) | ZDHHC7MAPTHSD17B10ALDH1A1CA1 | |
| SCHEMBL1415321 | 0.84 | ALDH1A1 (0.52) | ZDHHC7ALDH1A1ATMACHEHPGD | |
| SCHEMBL4821463 | 0.82 | ZDHHC7 (0.47) | ZDHHC7MAPTHSD17B10ALDH1A1CA1 | |
| SCHEMBL106430 | 0.82 | ZDHHC7 (0.47) | ZDHHC7CA1CA2SMN1; SMN2TSHR | |
| SCHEMBL12757785 | 0.80 | ZDHHC7 (0.57) | ZDHHC7ALDH1A1CA1CA2ATM | |
| SCHEMBL1557964 | 0.78 | ALDH1A1 (0.54) | MAPTALDH1A1ATMACHENPC1 | |
| SCHEMBL2719658 | 0.76 | ALDH1A1 (0.52) | ZDHHC7MAPTALDH1A1CA1CA2 | |
| SCHEMBL1415328 | 0.76 | ZDHHC7 (0.55) | ZDHHC7ALDH1A1CA1CA2ATM | |
| SCHEMBL25626566 | 0.76 | ALDH1A1 (0.44) | ZDHHC7ALDH1A1CA1CA2ATM | |
| SCHEMBL14616917 | 0.75 | ATM (0.44) | ZDHHC7ALDH1A1CA1CA2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615522-B2 | Lubricant or polymer additives of increased molecular weight, low volatility, low water extractability and low residual halogen are obtained by replacing the terminal halogen atoms in the polymers obtained by ATRP with the functionally effective group of a lubricant or polymer additive | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-11-10 | — | — | US | disclosed |
| US-7615522-B2 | Lubricant or polymer additives of increased molecular weight, low volatility, low water extractability and low residual halogen are obtained by replacing the terminal halogen atoms in the polymers obtained by ATRP with the functionally effective group of a lubricant or polymer additive | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-11-10 | — | — | US | disclosed |