Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415321 | 0.82 | ALDH1A1 (0.52) | ZDHHC7ALDH1A1ATMHPGDTSHR | |
| SCHEMBL13624472 | 0.82 | ZDHHC7 (0.49) | ZDHHC7ALDH1A1CA1CA2ATM | |
| SCHEMBL12757785 | 0.78 | ZDHHC7 (0.57) | ZDHHC7ALDH1A1CA1CA2ATM | |
| SCHEMBL16552423 | 0.78 | NAAA (0.44) | ZDHHC7ALDH1A1CA1CA2ATM | |
| SCHEMBL16638163 | 0.76 | ZDHHC7 (0.43) | ZDHHC7ALDH1A1CA1CA2ATM | |
| SCHEMBL11879637 | 0.75 | ALDH1A1 (0.48) | ZDHHC7ALDH1A1CA1CA2ATM | |
| SCHEMBL6679550 | 0.75 | ALDH1A1 (0.48) | ZDHHC7ALDH1A1ATMMAPTRAB9A | |
| SCHEMBL1415328 | 0.75 | ZDHHC7 (0.55) | ZDHHC7ALDH1A1CA1CA2ATM | |
| SCHEMBL2719658 | 0.75 | ALDH1A1 (0.52) | ZDHHC7ALDH1A1CA1CA2ATM | |
| SCHEMBL27541522 | 0.75 | ALDH1A1 (0.44) | ALDH1A1CA1CA2ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378079-B2 | Agents for imaging and diagnostic methods using them | NST NEUROSURVIVAL TECHNOLOGIES LTD. (IL) | 2008-05-27 | — | — | US | disclosed |
| US-20050276750-A1 | Agents for imaging and diagnostic methods using them | APOSENSE LTD. (IL) | 2005-12-15 | — | — | US | disclosed |
| EP-1546092-A2 | AGENTS FOR IMAGING AND DIAGNOSTIC METHODS USING THEM | Nst Neurosurvival Technologies Ltd. (IL) | 2005-06-29 | — | — | EP | disclosed |
| WO-2003101948-A2 | AGENTS FOR IMAGING AND DIAGNOSTIC METHODS USING THEM | NST NEUROSURVIVAL TECHNOLOGIES LTD. (IL) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050276750-A1 | Agents for imaging and diagnostic methods using them | ANXA4, ANXA3, NME4 | ZDHHC7 1982/4885ALDH1A1 4325/4885CA1 2721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.