Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.85 |
| ▸ | HPGD | P15428 | 11/20 | 0.85 |
| ▸ | MEN1 | O00255 | 3/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | HTT | P42858 | 3/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30565431 | 1.00 | KDM4E (0.85) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL31598298 | 0.96 | KDM4E (0.82) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4742405 | 0.96 | KDM4E (0.82) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL32667991 | 0.92 | KDM4E (1.00) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL31127004 | 0.87 | KDM4E (0.83) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| Pteryxin SCHEMBL31598386 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| Pteryxin SCHEMBL14511558 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| Pteryxin SCHEMBL14523890 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| Pteryxin SCHEMBL31614319 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| Pteryxin SCHEMBL30565449 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090292012-A1 | Therapeutic Agent | TAKARA BIO INC. (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090292012-A1 | Therapeutic Agent | TAKARA BIO INC. (JP) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090292012-A1 | Therapeutic Agent | LCAT, ACAT2, ACAT1 | KDM4E 3297/4885ALDH1A1 2201/4885HPGD 596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.