Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317729 | 1.00 | TSHR (0.45) | TSHRLMNASMN1; SMN2HPGDSLC6A4 | |
| SCHEMBL1436765 | 0.75 | HPGD (0.59) | TSHRLMNASMN1; SMN2HPGDSLC6A4 | |
| SCHEMBL7769417 | 0.75 | TSHR (0.53) | TSHRLMNASMN1; SMN2HPGDSLC6A4 | |
| Bromide SCHEMBL28304801 | 0.72 | HPGD (0.57) | TSHRLMNASMN1; SMN2HPGDSLC6A4 | |
| SCHEMBL10935253 | 0.72 | — | — | |
| SCHEMBL514060 | 0.70 | — | — | |
| SCHEMBL14920785 | 0.70 | — | — | |
| SCHEMBL5014006 | 0.70 | — | — | |
| SCHEMBL19374664 | 0.70 | — | — | |
| SCHEMBL15336732 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563675-B2 | Curable compositions composed of silanes with two hydrolyzable groups | HENKEL AG & CO. KGAA (DE) | 2013-10-22 | — | — | US | disclosed |
| US-8450411-B2 | Curable composition having a silane-modified reactive thinner | HENKEL AG & CO. KGAA (DE) | 2013-05-28 | — | — | US | disclosed |
| US-20120108730-A1 | CURABLE COMPOSITION HAVING A SILANE-MODIFIED REACTIVE THINNER | HENKEL AG & CO. KGAA (DE) | 2012-05-03 | — | — | US | disclosed |
| US-8067508-B2 | Compositions consisting of partially silyl-terminated polymers | HENKEL AG & CO. KGAA (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20100204387-A1 | CURABLE COMPOSITIONS COMPOSED OF SILANES WITH TWO HYDROLYZABLE GROUPS | HENKEL AG & CO. KGAA (DE) | 2010-08-12 | — | — | US | disclosed |
| US-20100143712-A1 | SILANE-CROSSLINKING ADHESIVE OR SEALANT COMPRISING N-SILYLALKYLAMIDES AND USE THEREOF | HENKEL AG & CO. KGAA (DE) | 2010-06-10 | — | — | US | disclosed |
| US-20100081757-A1 | COMPOSITIONS CONSISTING OF PARTIALLY SILYL-TERMINATED POLYMERS | HENKEL AG & CO. KGAA (DE) | 2010-04-01 | — | — | US | disclosed |