Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084404 | 0.88 | TSHR (0.47) | TSHRLMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL28355217 | 0.84 | L3MBTL1 (0.46) | TSHRLMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL1436765 | 0.81 | HPGD (0.59) | TSHRLMNASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL10935253 | 0.79 | — | — | |
| SCHEMBL29023320 | 0.78 | LMNA (0.44) | TSHRLMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL19374664 | 0.77 | — | — | |
| SCHEMBL14920785 | 0.77 | — | — | |
| SCHEMBL5014006 | 0.77 | — | — | |
| SCHEMBL15336732 | 0.77 | — | — | |
| SCHEMBL12541 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112179-A1 | MULTILAYER COMPOSITES | DYNEON LLC (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000013891-A1 | MULTILAYER COMPOSITES | DYNEON LLC (US) | 2000-03-16 | — | — | WO | disclosed |