SCHEMBL1436765

SCHEMBL1436765

Clc1ccccc1Oc1ccccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.59
SLC6A2 P23975 4/20 0.57
SLC6A4 P31645 4/20 0.57
SLC6A3 Q01959 4/20 0.57
CXCL8 P10145 1/20 0.55
LMNA P02545 2/20 0.53
TSHR P16473 1/20 0.53
RHEB Q15382 2/20 0.50
ALDH1A1 P00352 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CAMK2A Q9UQM7 1/20 0.46
KMT2A Q03164 1/20 0.46
HTR1A P08908 1/20 0.44
DPP4 P27487 1/20 0.43
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28304801 0.97 HPGD (0.57) HPGDSLC6A2SLC6A4SLC6A3CXCL8
Ethylene Glycol SCHEMBL3365161 0.87 CXCL8 (0.56) HPGDSLC6A2SLC6A4SLC6A3CXCL8
SCHEMBL7176453 0.86 DPP4 (0.53) HPGDSLC6A2SLC6A4SLC6A3CXCL8
SCHEMBL11818090 0.85 HPGD (0.48) HPGDSLC6A2SLC6A4SLC6A3CXCL8
SCHEMBL9056153 0.85 CXCL8 (0.50) HPGDSLC6A2SLC6A4SLC6A3CXCL8
SCHEMBL23406375 0.85 HPGD (0.48) HPGDSLC6A2SLC6A4SLC6A3CXCL8
SCHEMBL11420853 0.85 AR (0.59) HPGDSLC6A2SLC6A4SLC6A3CXCL8
SCHEMBL1862821 0.85 CXCL8 (0.50) HPGDSLC6A2SLC6A4SLC6A3CXCL8
SCHEMBL9266509 0.85 TSHR (0.54) HPGDSLC6A2SLC6A4SLC6A3CXCL8
SCHEMBL5541601 0.85 HPGD (0.48) HPGDSLC6A2SLC6A4SLC6A3CXCL8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118975944-A Exfoliating and skin tendering essence and preparation method thereof 广东格烯生物科技股份有限公司 2024-11-19 CN claimed
CN-113785838-B Combination fungicides containing chlorophenoxyamide and procymidone 浙江农林大学 2022-11-22 CN claimed
CN-108451145-B Cosmetic with arched mesh net 蔻诗曼嘉韩国股份公司 2021-06-29 CN claimed
CN-111631216-A Antimicrobial compositions 西姆莱斯股份公司 2020-09-08 CN claimed
CN-105025712-B Antimicrobial compositions 西姆莱斯股份公司 2020-05-05 CN claimed
CN-110693754-A Antibacterial and anti-inflammatory pyridone composition and cosmetic containing same 烟台东方化学有限公司 2020-01-17 CN claimed
CN-110664658-A Whitening antibacterial composition and cosmetic containing same 菏泽新东方日化科技有限公司 2020-01-10 CN claimed
EP-2699088-A2 COATING COMPOSITIONS FOR PATHOGEN CONTROL IN VEGETABLES Exosect Limited (GB) 2014-02-26 EP claimed
WO-2012143678-A2 COATING COMPOSITIONS FOR PATHOGEN CONTROL IN VEGETABLES EXOSECT LIMITED (GB) 2012-10-26 WO claimed
CN-100441575-C Process for preparation of cyclid esters and method for purification of the same KUREHA CHEMICAL IND CO LTD (JP) 2008-12-10 CN claimed
CN-1446209-A Process for preparation of cyclid esters and method for purification of the same KUREHA CHEMICAL IND CO LTD (JP) 2003-10-01 CN claimed
US-6391941-B1 Antimicrobial therapeutic putty MAGISTER CORPORATION 2002-05-21 US claimed
CN-122060245-A Antistatic resin composition 东邦化学工业株式会社 2026-05-19 CN disclosed
CN-119868210-A Anti-wrinkle combined oil and application thereof 广州名门闺秀生物科技有限责任公司 2025-04-25 CN disclosed
CN-119733116-A Synthetic elastomer articles and methods of producing the same 皮肤防护有限公司 2025-04-01 CN disclosed
CN-119591881-A Polyether organic silicon copolymer containing star polyether, and preparation method and application thereof 江苏美思德化学股份有限公司 2025-03-11 CN disclosed
US-4158088-A MODIFIED TITANIUM COMPONENT MITSUI TOATSU CHEMICALS, INC. (JP) 1979-06-12 US disclosed
US-RE29617-E Aryl methylene polymers prepared from chloral, bromal or glyoxalic acid GENERAL ELECTRIC COMPANY (US) 1978-04-25 US disclosed
US-4028481-A ACTIVATED TITANIUM TRICHLORIDE AND AN ORGANOALUMINUM COMPOUND MITSUI TOATSU CHEMICALS, INCORPORATED (JA) 1977-06-07 US disclosed
US-3939084-A Functional fluid compositions containing substituted pyrimidines MONSANTO COMPANY (US) 1976-02-17 US disclosed