Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11912167 | 0.76 | CA12 (0.43) | TDP1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8521796 | 0.76 | POLB (0.43) | TDP1IDO1ALDH1A1L3MBTL1POLB | |
| SCHEMBL23428723 | 0.76 | MAPT (0.39) | LMNACYP1A2CYP2D6CYP2C9CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL27844308 | 0.74 | CA12 (0.42) | TDP1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27739040 | 0.74 | CA12 (0.42) | TDP1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13952007 | 0.73 | TDP1 (0.36) | TDP1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14273549 | 0.73 | NPC1 (0.38) | LMNAALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL1537798 | 0.73 | ALDH1A1 (0.52) | TDP1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL31484713 | 0.73 | ALDH1A1 (0.52) | TDP1LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL19827908 | 0.71 | IDO1 (0.40) | TDP1LMNACYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220030868-A1 | FUNGICIDAL HALOMETHYL KETONES AND HYDRATES | FMC CORPORATION | 2022-02-03 | — | — | US | disclosed |
| EP-1961052-B1 | ORGANIC SEMICONDUCTORS AND THEIR MANUFACTURE | BASF SE (DE) | 2013-03-06 | — | — | EP | disclosed |
| WO-2009136995-A2 | INHIBITORS OF SYK PROTEIN KINASE | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |
| EP-2065386-A1 | CGRP antagonists | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-2062889-A1 | Compounds | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008140792-A1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220030868-A1 | FUNGICIDAL HALOMETHYL KETONES AND HYDRATES | TUBA1A, TTBK1, TUBA1B | TDP1 732/4885LMNA 1413/4885CYP1A2 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.