Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13283105 | 0.80 | KDM4E (0.41) | TDP1L3MBTL1ALDH1A1POLBSIGMAR1 | |
| SCHEMBL24916381 | 0.77 | IDO1 (0.40) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4465102 | 0.75 | NPC1 (0.41) | TDP1L3MBTL1ALDH1A1GAANPC1 | |
| SCHEMBL13624671 | 0.73 | TDP1 (0.40) | TDP1L3MBTL1ALDH1A1CA12CA1 | |
| SCHEMBL11912167 | 0.73 | CA12 (0.43) | TDP1L3MBTL1ALDH1A1CA12CA1 | |
| Ammonia Solution, Strong SCHEMBL27844308 | 0.71 | CA12 (0.42) | TDP1L3MBTL1ALDH1A1CA12CA1 | |
| SCHEMBL27739040 | 0.71 | CA12 (0.42) | TDP1L3MBTL1ALDH1A1CA12CA1 | |
| SCHEMBL14366502 | 0.70 | L3MBTL1 (0.71) | TDP1L3MBTL1ALDH1A1SIGMAR1GRIN2D | |
| SCHEMBL1537798 | 0.69 | ALDH1A1 (0.52) | TDP1L3MBTL1ALDH1A1CA12CA1 | |
| SCHEMBL31484713 | 0.69 | ALDH1A1 (0.52) | TDP1L3MBTL1ALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7494698-B2 | Polymers with high internal free volume | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-02-24 | — | — | US | disclosed |