Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nortopsentin D SCHEMBL29489921 | 0.81 | PDGFRB (0.62) | PDGFRBMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4398433 | 0.79 | MAPT (0.62) | PDGFRBMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4400158 | 0.79 | PDGFRB (0.56) | PDGFRBMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL25034150 | 0.78 | TUBB4A (0.68) | PDGFRBMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17179315 | 0.78 | TUBB4A (0.63) | PDGFRBMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11960986 | 0.77 | PDGFRB (0.47) | PDGFRBALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14300518 | 0.77 | CYP1A2 (0.46) | PDGFRBMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL25034151 | 0.76 | PDGFRB (1.00) | PDGFRBMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL25034156 | 0.75 | MAPT (0.57) | PDGFRBMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL13963152 | 0.75 | HTR1B (0.44) | PDGFRBMAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615638-B2 | Synthesis of grossularines-1 and analogs thereof and method of use | CITY OF HOPE (US) | 2009-11-10 | — | — | US | disclosed |