Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.49 |
| ▸ | SAT1 | P21673 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22323199 | 0.91 | SAT1 (0.56) | GNAI3GNAO1GNAI1SAT1EPHX1 | |
| SCHEMBL3427404 | 0.84 | — | — | |
| SCHEMBL13625268 | 0.84 | SAT1 (0.50) | GNAI3GNAO1GNAI1SAT1EPHX1 | |
| SCHEMBL13625269 | 0.84 | GNAI3 (0.69) | GNAI3GNAO1GNAI1SAT1EPHX1 | |
| SCHEMBL15700835 | 0.84 | GNAI3 (0.69) | GNAI3GNAO1GNAI1SAT1EPHX1 | |
| SCHEMBL11067343 | 0.83 | EPHX1 (0.47) | GNAI3GNAO1GNAI1SAT1EPHX1 | |
| SCHEMBL7201201 | 0.82 | SAT1 (0.67) | GNAI3GNAO1GNAI1SAT1CA2 | |
| SCHEMBL7207732 | 0.82 | SAT1 (0.67) | GNAI3GNAO1GNAI1SAT1CA2 | |
| SCHEMBL7202980 | 0.82 | SAT1 (0.67) | GNAI3GNAO1GNAI1SAT1CA2 | |
| SCHEMBL7206783 | 0.82 | SAT1 (0.67) | GNAI3GNAO1GNAI1SAT1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138511-A1 | LONG-ACTING Y2 AND/OR Y4 RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2009-11-19 | — | — | WO | disclosed |