Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAT1 | P21673 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22323199 | 0.88 | SAT1 (0.56) | SAT1GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL13624910 | 0.84 | GNAI3 (0.49) | SAT1GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL3427404 | 0.81 | — | — | |
| SCHEMBL11067343 | 0.80 | EPHX1 (0.47) | SAT1GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL7202980 | 0.79 | SAT1 (0.67) | SAT1GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL7206783 | 0.79 | SAT1 (0.67) | SAT1GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL7201201 | 0.79 | SAT1 (0.67) | SAT1GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL7207732 | 0.79 | SAT1 (0.67) | SAT1GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL7199454 | 0.79 | SAT1 (0.67) | SAT1GNAI3GNAO1GNAI1CA12 | |
| SCHEMBL11064531 | 0.78 | SAT1 (0.45) | SAT1GNAI3GNAO1GNAI1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138511-A1 | LONG-ACTING Y2 AND/OR Y4 RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2009-11-19 | — | — | WO | disclosed |