Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NAAA | Q02083 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1690703 | 0.95 | EPHX1 (0.69) | EPHX1EPHX2NAAA | |
| SCHEMBL7181896 | 0.90 | EPHX1 (0.60) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22289771 | 0.84 | NAAA (0.59) | EPHX1RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL1171950 | 0.84 | EPHX1 (0.72) | EPHX1EPHX2RAB9ANPC1NAAA | |
| SCHEMBL15975484 | 0.83 | EPHX1 (0.71) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8393719 | 0.82 | EPHX1 (0.84) | EPHX1EPHX2RAB9ATSHRALDH1A1 | |
| SCHEMBL1424064 | 0.82 | EPHX1 (0.84) | EPHX1EPHX2RAB9ATSHRALDH1A1 | |
| Bicarbonate SCHEMBL6203780 | 0.81 | EPHX1 (0.82) | EPHX1EPHX2RAB9ATSHRALDH1A1 | |
| SCHEMBL8392063 | 0.81 | NPC1 (0.55) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8395708 | 0.81 | NPC1 (0.55) | EPHX1EPHX2RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |
| EP-1670852-B1 | THERMOSETTING MATERIAL BASED ON ANTIPLASTICIZED POLYTHIOURETHANE, AND OPHTHALMIC LENS COMPRISING AN ANTIPLASTICIZED THERMOSETTING MATERIAL | ESSILOR INT (FR) | 2008-12-10 | — | — | EP | disclosed |