Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171950 | 0.88 | EPHX1 (0.72) | EPHX1HPGDRAB9ACYP1A2CYP2C19 | |
| SCHEMBL1690703 | 0.86 | EPHX1 (0.69) | EPHX1NAAAEPHX2 | |
| SCHEMBL12196002 | 0.83 | EPHX1 (1.00) | EPHX1HPGDMEN1KMT2ANAAA | |
| SCHEMBL13625190 | 0.83 | EPHX1 (0.65) | EPHX1RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL13625188 | 0.79 | EPHX1 (0.78) | EPHX1RAB9ASMN1; SMN2NPC1CYP3A4 | |
| SCHEMBL21059112 | 0.76 | EPHX1 (0.69) | EPHX1SMN1; SMN2NAAAEPHX2 | |
| SCHEMBL22289771 | 0.75 | NAAA (0.59) | EPHX1RAB9ASMN1; SMN2NPC1NAAA | |
| SCHEMBL7181896 | 0.75 | EPHX1 (0.60) | EPHX1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28059725 | 0.75 | EPHX1 (0.68) | EPHX1SMN1; SMN2NAAAEPHX2 | |
| SCHEMBL1690687 | 0.75 | EPHX1 (0.68) | EPHX1SMN1; SMN2NAAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815951-B2 | Inhibitors of epoxide hydrolases for the treatment of inflammation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-26 | — | — | US | disclosed |