Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.53 |
| ▸ | GNPAT | O15228 | 1/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 3/20 | 0.41 |
| ▸ | FNTB | P49356 | 3/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625464 | 0.95 | FOLH1 (0.59) | FOLH1GNPATSLC6A5NOD1CPB2 | |
| SCHEMBL27739688 | 0.95 | FOLH1 (0.59) | FOLH1GNPATSLC6A5NOD1CPB2 | |
| SCHEMBL13625380 | 0.89 | GNPAT (0.47) | FOLH1GNPATSLC6A5NOD1FNTA | |
| SCHEMBL30834826 | 0.87 | FOLH1 (0.57) | FOLH1GNPATSLC6A5NOD1CPB2 | |
| SCHEMBL4649464 | 0.86 | SLC6A5 (0.51) | FOLH1GNPATSLC6A5NOD1CPB2 | |
| SCHEMBL4649465 | 0.86 | SLC6A5 (0.51) | FOLH1GNPATSLC6A5NOD1CPB2 | |
| SCHEMBL20880031 | 0.86 | FOLH1 (0.51) | FOLH1GNPATSLC6A5NOD1CPB2 | |
| SCHEMBL13471898 | 0.85 | SLC6A5 (0.41) | FOLH1GNPATSLC6A5NOD1CPB2 | |
| SCHEMBL1533875 | 0.84 | GNPAT (0.73) | FOLH1GNPATSLC6A5NOD1 | |
| SCHEMBL928640 | 0.83 | GNPAT (0.47) | FOLH1GNPATSLC6A5NOD1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937048-B2 | Anti-angiogenic compounds | COVX TECHNOLOGIES IRELAND, LIMITED (IE) | 2015-01-20 | — | — | US | disclosed |
| WO-2009136352-A1 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND, LTD. (IE) | 2009-11-12 | — | — | WO | disclosed |