Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.59 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.57 |
| ▸ | GNPAT | O15228 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27739688 | 1.00 | FOLH1 (0.59) | FOLH1SLC6A5GNPATNOD1CPB2 | |
| SCHEMBL13625463 | 0.95 | FOLH1 (0.53) | FOLH1SLC6A5GNPATNOD1CPB2 | |
| SCHEMBL232587 | 0.88 | SLC6A5 (0.65) | FOLH1SLC6A5GNPATNOD1CPB2 | |
| SCHEMBL482959 | 0.88 | FOLH1 (0.65) | FOLH1SLC6A5GNPATNOD1CPB2 | |
| SCHEMBL4272196 | 0.88 | FOLH1 (0.65) | FOLH1SLC6A5GNPATNOD1CPB2 | |
| SCHEMBL232527 | 0.88 | SLC6A5 (0.65) | FOLH1SLC6A5GNPATNOD1CPB2 | |
| SCHEMBL13625380 | 0.88 | GNPAT (0.47) | FOLH1SLC6A5GNPATNOD1FNTA | |
| SCHEMBL18104611 | 0.87 | HPGDS (0.44) | FOLH1SLC6A5GNPATNOD1CPB2 | |
| SCHEMBL1681307 | 0.86 | FOLH1 (0.58) | FOLH1SLC6A5GNPATNOD1CPB2 | |
| SCHEMBL7027662 | 0.86 | SLC6A5 (0.72) | FOLH1SLC6A5GNPATNOD1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937048-B2 | Anti-angiogenic compounds | COVX TECHNOLOGIES IRELAND, LIMITED (IE) | 2015-01-20 | — | — | US | disclosed |
| WO-2009136352-A1 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND, LTD. (IE) | 2009-11-12 | — | — | WO | disclosed |
| CN-101296708-A | Selective VPAC2 receptor peptide agonists | LILLY CO ELI (US) | 2008-10-29 | — | — | CN | disclosed |