⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13223640 | 0.75 | — | — | |
| SCHEMBL471969 | 0.75 | — | — | |
| SCHEMBL2021157 | 0.71 | LMNA (0.33) | — | |
| SCHEMBL471976 | 0.71 | SLC22A6 (0.33) | — | |
| SCHEMBL941351 | 0.71 | — | — | |
| SCHEMBL4360725 | 0.71 | — | — | |
| SCHEMBL3167705 | 0.71 | — | — | |
| SCHEMBL11527926 | 0.71 | — | — | |
| SCHEMBL482641 | 0.71 | — | — | |
| SCHEMBL11860907 | 0.69 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137739-A1 | PROCESSES FOR THE PREPARATION OF O-[5-[4-AMINO-THIAZOL-2-YL]-PYRIDIN-2-YLMETHYL]-HYDROXYLAMINE | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |