SCHEMBL3167705

SCHEMBL3167705

O=C=NC(=O)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11467408 0.78
SCHEMBL13223640 0.75
SCHEMBL471969 0.75
SCHEMBL3181631 0.74
SCHEMBL471976 0.71 SLC22A6 (0.33)
SCHEMBL941351 0.71
SCHEMBL13625592 0.71
SCHEMBL11527926 0.71
SCHEMBL2021157 0.71 LMNA (0.33)
SCHEMBL482641 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100022415-A1 ACTIVE CARRIER, ITS PRODUCTION AND ITS USE AVICOR KET. (HU) 2010-01-28 US claimed
EP-2080026-A1 ACTIVE CARRIER, ITS PRODUCTION AND ITS USE Avicor Kft. (HU) 2009-07-22 EP claimed
WO-2008023208-A1 ACTIVE CARRIER, ITS PRODUCTION AND ITS USE AVICOR KFT. (HU) 2008-02-28 WO claimed
JP-9025268-A None JP disclosed
CN-118878517-A ANXA3 protein targeted degradation chimeric body and preparation method and application thereof 复旦大学 2024-11-01 CN disclosed
US-7842813-B2 for synthesis of erythromycin derivatives; reacting thionyl chloride with 6-hydroxylmethyl-nicotinic acid methyl ester to provide 6-chloromethyl-nicotinic acid methyl ester, chlorinating, reacting with ammonia or ammonium hydroxide, sulfiding ENANTA PHARMACEUTICALS, INC. (US) 2010-11-30 US disclosed
US-7842813-B2 for synthesis of erythromycin derivatives; reacting thionyl chloride with 6-hydroxylmethyl-nicotinic acid methyl ester to provide 6-chloromethyl-nicotinic acid methyl ester, chlorinating, reacting with ammonia or ammonium hydroxide, sulfiding ENANTA PHARMACEUTICALS, INC. (US) 2010-11-30 US disclosed
US-20100022415-A1 ACTIVE CARRIER, ITS PRODUCTION AND ITS USE AVICOR KET. (HU) 2010-01-28 US disclosed
US-20090281324-A1 PROCESSES FOR THE PREPARATION OF O-[5-(4-AMINO-THIAZOL-2-YL)-PYRIDIN-2-YLMETHYL]-HYDROXYLAMINE ENANTA PHARMACEUTICALS, INC. 2009-11-12 US disclosed
US-20090281324-A1 PROCESSES FOR THE PREPARATION OF O-[5-(4-AMINO-THIAZOL-2-YL)-PYRIDIN-2-YLMETHYL]-HYDROXYLAMINE ENANTA PHARMACEUTICALS, INC. 2009-11-12 US disclosed
EP-2080026-A1 ACTIVE CARRIER, ITS PRODUCTION AND ITS USE Avicor Kft. (HU) 2009-07-22 EP disclosed
WO-2008023208-A1 ACTIVE CARRIER, ITS PRODUCTION AND ITS USE AVICOR KFT. (HU) 2008-02-28 WO disclosed
JP-H0925268-A 2-NITROIMIDAZOLE DERIVATIVE TAIHO YAKUHIN KOGYO KK 1997-01-28 JP disclosed
JP-H00925268-A 0001-01-01 JP disclosed