Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558598 | 0.82 | IDO1 (0.53) | IDO1TDP1KDM4EALDH1A1MAPT | |
| SCHEMBL29590253 | 0.75 | IDO1 (0.59) | IDO1CHRM4DRD2HTR7FFAR1 | |
| SCHEMBL11142136 | 0.75 | IDO1 (0.59) | IDO1CHRM4DRD2HTR7FFAR1 | |
| SCHEMBL14062665 | 0.75 | ALDH1A1 (0.47) | IDO1ALDH1A1MAPTKMT2AFFAR1 | |
| SCHEMBL8308445 | 0.74 | IDO1 (0.58) | IDO1TDP1KDM4EALDH1A1MAPT | |
| SCHEMBL9722001 | 0.73 | IDO1 (0.55) | IDO1KDM4EALDH1A1KMT2AFFAR1 | |
| SCHEMBL30908530 | 0.72 | IDO1 (0.56) | IDO1CHRM4DRD2HTR7FFAR1 | |
| SCHEMBL2175357 | 0.72 | IDO1 (0.61) | IDO1CHRM4DRD2HTR7FFAR1 | |
| SCHEMBL817976 | 0.72 | IDO1 (0.56) | IDO1CHRM4DRD2HTR7FFAR1 | |
| SCHEMBL1455049 | 0.72 | IDO1 (0.56) | IDO1CHRM4DRD2HTR7FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |