Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1891503 | 0.87 | AGTR1 (0.35) | AGTR1PPARGACHE | |
| SCHEMBL1893894 | 0.86 | AGTR1 (0.34) | AGTR1PPARGACHE | |
| SCHEMBL14208518 | 0.85 | AGTR1 (0.32) | AGTR1 | |
| SCHEMBL1890118 | 0.83 | AGTR1 (0.32) | AGTR1PPARGACHE | |
| SCHEMBL1890705 | 0.82 | AGTR1 (0.38) | AGTR1GSK3BPPARGACHE | |
| SCHEMBL1895963 | 0.82 | AGTR1 (0.36) | AGTR1PPARGACHE | |
| SCHEMBL1891217 | 0.78 | ACHE (0.40) | AGTR1ACHE | |
| SCHEMBL1888990 | 0.78 | AGTR1 (0.36) | AGTR1PPARGACHE | |
| SCHEMBL1894687 | 0.77 | PPARG (0.38) | AGTR1PPARG | |
| SCHEMBL1886294 | 0.77 | PPARG (0.38) | AGTR1GSK3BPPARGACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |