Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | YWHAH | Q04917 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1178262 | 0.88 | GPR6 (0.35) | PPARGPTGDR2 | |
| SCHEMBL1178260 | 0.88 | GPR6 (0.35) | PPARGPTGDR2 | |
| SCHEMBL13563275 | 0.83 | PTGDR2 (0.37) | PTGDR2 | |
| SCHEMBL1179379 | 0.79 | EGLN2 (0.34) | PTGDR2DRD2 | |
| SCHEMBL1179381 | 0.79 | EGLN2 (0.34) | PTGDR2DRD2 | |
| SCHEMBL14218047 | 0.79 | PTGDR2 (0.32) | PTGDR2 | |
| SCHEMBL12640978 | 0.78 | RET (0.32) | PTGDR2HTR6DRD2 | |
| SCHEMBL1420698 | 0.77 | GPR6 (0.37) | PPARGPTGDR2ADAM17 | |
| SCHEMBL13626057 | 0.77 | CYP2C19 (0.32) | PTGDR2DRD2 | |
| SCHEMBL12640885 | 0.76 | PTGDR2 (0.30) | PTGDR2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140448-A1 | TETRAHYDROCYCLOPENTA[B]INDOLE ANDROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |