Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 6/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 7/20 | 0.37 |
| ▸ | CNR1 | P21554 | 6/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10021102 | 0.85 | MLYCD (0.41) | NR1H2NR1H3NR1I2CNR2CNR1 | |
| SCHEMBL14304743 | 0.85 | NR1H2 (0.41) | NR1H2NR1H3NR1I2CNR2CNR1 | |
| SCHEMBL11929875 | 0.83 | ALDH1A1 (0.45) | NR1H2NR1H3NR1I2 | |
| SCHEMBL12013419 | 0.81 | CYP2D6 (0.40) | NR1H2NR1H3NR1I2CNR2CNR1 | |
| SCHEMBL2798326 | 0.80 | NR1H2 (0.36) | NR1H2NR1H3NR1I2CNR2CNR1 | |
| SCHEMBL16799888 | 0.78 | NR1H2 (0.41) | NR1H2NR1H3NR1I2CNR2CNR1 | |
| SCHEMBL16546589 | 0.77 | CNR2 (0.41) | CNR2CNR1ESR1ESR2 | |
| SCHEMBL18595674 | 0.76 | TRPV1 (0.37) | NR1H2NR1H3NR1I2ESR1ESR2 | |
| SCHEMBL18275128 | 0.74 | SRD5A2 (0.45) | NR1H2NR1I2 | |
| SCHEMBL16799610 | 0.70 | NR1H2 (0.46) | NR1H2NR1H3NR1I2CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142967-A1 | THERAPEUTIC PROSTAGLANDIN COMPOUNDS USED AS OCULAR HYPOTENSIVE AGENTS | ALLERGAN, INC. (US) | 2009-11-26 | — | — | WO | disclosed |