Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | BTK | Q06187 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626627 | 0.90 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTLMNAL3MBTL1HDAC1 | |
| SCHEMBL13626450 | 0.89 | SMN1; SMN2 (0.70) | SMN1; SMN2HTTLMNAL3MBTL1HDAC1 | |
| SCHEMBL13626616 | 0.86 | RAB9A (0.75) | SMN1; SMN2HTTLMNAL3MBTL1HDAC1 | |
| SCHEMBL30530313 | 0.85 | HDAC1 (0.62) | SMN1; SMN2HTTLMNAL3MBTL1HDAC1 | |
| SCHEMBL15165561 | 0.84 | HDAC1 (0.61) | SMN1; SMN2HTTLMNAL3MBTL1HDAC1 | |
| SCHEMBL12666635 | 0.84 | CYP2C9 (0.61) | SMN1; SMN2HTTLMNAL3MBTL1HDAC1 | |
| SCHEMBL24398080 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTLMNAL3MBTL1HDAC1 | |
| SCHEMBL27964239 | 0.81 | HDAC6 (0.55) | SMN1; SMN2HTTLMNAL3MBTL1HDAC1 | |
| SCHEMBL28300862 | 0.81 | BTK (0.68) | SMN1; SMN2LMNAL3MBTL1HDAC1HDAC6 | |
| SCHEMBL13747820 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAHDAC6ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138440-A1 | CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-11-19 | — | — | WO | disclosed |