Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.70 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | GALR3 | O60755 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | STAT3 | P40763 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626627 | 0.89 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL13626450 | 0.88 | SMN1; SMN2 (0.70) | RAB9ASMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL12674139 | 0.87 | RAB9A (0.73) | RAB9AHIF1AEPAS1SMN1; SMN2LMNA | |
| SCHEMBL13626446 | 0.86 | SMN1; SMN2 (0.71) | RAB9ASMN1; SMN2LMNAMAPTTSHR | |
| SCHEMBL30530297 | 0.86 | SMN1; SMN2 (0.64) | RAB9AHIF1AEPAS1SMN1; SMN2LMNA | |
| SCHEMBL12273973 | 0.86 | SMN1; SMN2 (0.64) | RAB9AHIF1AEPAS1SMN1; SMN2LMNA | |
| SCHEMBL3558274 | 0.85 | HDAC1 (0.71) | RAB9AHIF1AEPAS1MAPTTSHR | |
| SCHEMBL12666637 | 0.85 | RAB9A (0.71) | RAB9AHIF1AEPAS1SMN1; SMN2LMNA | |
| SCHEMBL8710661 | 0.85 | RAB9A (0.71) | RAB9AHIF1AEPAS1SMN1; SMN2LMNA | |
| SCHEMBL21657710 | 0.82 | HIF1A (1.00) | RAB9AHIF1AEPAS1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138440-A1 | CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-11-19 | — | — | WO | disclosed |