Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626553 | 1.00 | F10 (0.61) | F10CFTR | |
| SCHEMBL13626556 | 0.92 | F10 (0.55) | F10CFTR | |
| SCHEMBL13626565 | 0.90 | F10 (0.56) | F10CFTR | |
| SCHEMBL4605676 | 0.88 | F10 (0.76) | F10 | |
| SCHEMBL4604418 | 0.88 | F10 (0.78) | F10 | |
| SCHEMBL4606847 | 0.88 | F10 (0.78) | F10 | |
| SCHEMBL13626567 | 0.87 | F10 (0.52) | F10CFTR | |
| SCHEMBL4606642 | 0.84 | F10 (0.54) | F10 | |
| SCHEMBL4605212 | 0.84 | F10 (0.54) | F10 | |
| SCHEMBL13626557 | 0.82 | F10 (0.46) | F10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612089-B2 | Tetrahydroisoquinolines as factor Xa inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7612089-B2 | Tetrahydroisoquinolines as factor Xa inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |