SCHEMBL13626687

SCHEMBL13626687

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nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FUCA1 P04066 1/20 0.33
▸ OGA O60502 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15369785 1.00 FUCA1 (0.33) FUCA1OGA
SCHEMBL19565361 1.00 FUCA1 (0.33) FUCA1OGA
SCHEMBL26369274 0.93 FUCA1 (0.32) FUCA1OGA
SCHEMBL26369256 0.93 FUCA1 (0.32) FUCA1OGA
SCHEMBL26369286 0.93 FUCA1 (0.32) FUCA1OGA
SCHEMBL12371022 0.93 FUCA1 (0.32) FUCA1OGA
SCHEMBL26369295 0.93 FUCA1 (0.32) FUCA1OGA
SCHEMBL12371038 0.93 FUCA1 (0.32) FUCA1OGA
SCHEMBL26369280 0.93 FUCA1 (0.32) FUCA1OGA
SCHEMBL26369259 0.93 FUCA1 (0.32) FUCA1OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160220595-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO DEFENSE THREAT REDUCTION AGENCY, US DOD 2016-08-04 — — US disclosed
US-20090280567-A1 STABILIZED SIRNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS DHARMACON, INC. (US) 2009-11-12 — — US disclosed
US-20090197332-A1 Modified Short Interfering RNA QIAGEN GMBH (DE) 2009-08-06 — — US disclosed
US-20070269889-A1 Stabilized siRNAs as transfection controls and silencing reagents DHARMACON, INC. (US) 2007-11-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160220595-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO PNP, NTPCR, TYMP FUCA1 1162/4885OGA 1137/4885
US-20090197332-A1 Modified Short Interfering RNA NSUN2, NSUN3, METTL16 FUCA1 479/4885OGA 333/4885
US-20090280567-A1 STABILIZED SIRNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS PHAX, NSUN2, UPF1 FUCA1 523/4885OGA 200/4885
US-20070269889-A1 Stabilized siRNAs as transfection controls and silencing reagents PHAX, NSUN2, UPF1 FUCA1 523/4885OGA 200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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