Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250357 | 1.00 | HTR2C (0.38) | HTR2C | |
| SCHEMBL13627326 | 0.83 | HTR2C (0.33) | HTR2C | |
| SCHEMBL4483043 | 0.83 | HTR2C (0.33) | HTR2C | |
| SCHEMBL4477342 | 0.82 | TRPA1 (0.36) | HTR2C | |
| SCHEMBL4472523 | 0.82 | TRPA1 (0.36) | HTR2C | |
| SCHEMBL13627313 | 0.82 | TRPA1 (0.36) | HTR2C | |
| SCHEMBL13627311 | 0.79 | HTR2C (0.40) | HTR2C | |
| SCHEMBL4250880 | 0.79 | HTR2C (0.40) | HTR2C | |
| SCHEMBL4479389 | 0.79 | CYP1A1 (0.35) | HTR2C | |
| SCHEMBL13627320 | 0.79 | CYP1A1 (0.35) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618980-B2 | Pyrrolo(oxo)quinolines as 5HT ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-17 | — | — | US | disclosed |