Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 16/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 9/20 | 0.33 |
| ▸ | HTR2B | P41595 | 9/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4478534 | 1.00 | HTR2C (0.37) | HTR2CALDH1A1MAPTHTR2AHTR2B | |
| SCHEMBL4248733 | 1.00 | HTR2C (0.37) | HTR2CALDH1A1MAPTHTR2AHTR2B | |
| SCHEMBL13627309 | 0.81 | HTR2C (0.41) | HTR2CHTR2AHTR2B | |
| SCHEMBL4248280 | 0.81 | HTR2C (0.41) | HTR2CHTR2AHTR2B | |
| SCHEMBL13627326 | 0.77 | HTR2C (0.33) | HTR2CALDH1A1MAPTHTR2AHTR2B | |
| SCHEMBL4483043 | 0.77 | HTR2C (0.33) | HTR2CALDH1A1MAPTHTR2AHTR2B | |
| SCHEMBL5675008 | 0.75 | HTR2C (0.40) | HTR2CALDH1A1MAPTHTR2AHTR2B | |
| SCHEMBL13627321 | 0.74 | HTR2C (0.47) | HTR2CALDH1A1HTR2AHTR2B | |
| SCHEMBL4246700 | 0.74 | HTR2C (0.47) | HTR2CALDH1A1HTR2AHTR2B | |
| SCHEMBL4482316 | 0.73 | CHRNA4 (0.33) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618980-B2 | Pyrrolo(oxo)quinolines as 5HT ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-17 | — | — | US | disclosed |