Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469750 | 1.00 | HTR2C (0.42) | HTR2CAHRMAPTHPGDCHRNB2 | |
| SCHEMBL13627311 | 0.85 | HTR2C (0.40) | HTR2CAHR | |
| SCHEMBL4250880 | 0.85 | HTR2C (0.40) | HTR2CAHR | |
| SCHEMBL4480129 | 0.78 | HTR2C (0.33) | HTR2CCHRNB2CHRNA4 | |
| SCHEMBL4476756 | 0.78 | HTR2C (0.33) | HTR2CCHRNB2CHRNA4 | |
| SCHEMBL13627328 | 0.78 | HTR2C (0.33) | HTR2CCHRNB2CHRNA4 | |
| SCHEMBL4483043 | 0.77 | HTR2C (0.33) | HTR2CMAPTCHRNA4 | |
| SCHEMBL13627326 | 0.77 | HTR2C (0.33) | HTR2CMAPTCHRNA4 | |
| SCHEMBL6216628 | 0.77 | MAPK1 (0.36) | HTR2CAHR | |
| SCHEMBL4482328 | 0.74 | TRPA1 (0.42) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618980-B2 | Pyrrolo(oxo)quinolines as 5HT ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-17 | — | — | US | disclosed |