Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26043679 | 0.97 | EPHX1 (0.62) | EPHX1TDP1GAAMEN1KMT2A | |
| SCHEMBL24435431 | 0.95 | EPHX1 (0.65) | EPHX1TDP1GAAMEN1KMT2A | |
| SCHEMBL12894206 | 0.95 | EPHX1 (0.65) | EPHX1TDP1GAAMEN1KMT2A | |
| SCHEMBL24435259 | 0.94 | EPHX1 (0.58) | EPHX1TDP1GAAMEN1KMT2A | |
| SCHEMBL851615 | 0.94 | TDP1 (0.56) | EPHX1TDP1GAAMEN1KMT2A | |
| SCHEMBL5416045 | 0.90 | EPHX1 (0.70) | EPHX1TDP1GAAMEN1KMT2A | |
| SCHEMBL5113769 | 0.89 | EPHX1 (0.73) | EPHX1TDP1GAAMEN1KMT2A | |
| SCHEMBL19263939 | 0.87 | EPHX1 (0.66) | EPHX1TDP1GAAMEN1KMT2A | |
| SCHEMBL15284931 | 0.87 | EPHX1 (0.55) | EPHX1TDP1GAAMEN1KMT2A | |
| SCHEMBL17733780 | 0.86 | EPHX1 (0.54) | EPHX1TDP1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009135842-A1 | AZETIDINES AND CYCLOBUTANES AS HISTAMINE H3 RECEPTOR ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2009-11-12 | — | — | WO | disclosed |