Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.54 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 5/20 | 0.42 |
| ▸ | ACACA | Q13085 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627401 | 0.86 | EPHX1 (0.62) | EPHX1CXCR4GAAKMT2AHDAC4 | |
| SCHEMBL24435431 | 0.85 | EPHX1 (0.65) | EPHX1CXCR4GAAKMT2AHDAC4 | |
| SCHEMBL12894206 | 0.85 | EPHX1 (0.65) | EPHX1CXCR4GAAKMT2AHDAC4 | |
| SCHEMBL9885049 | 0.84 | EPHX1 (0.42) | EPHX1PBKGAAKMT2ADRD2 | |
| SCHEMBL13683504 | 0.84 | EPHX1 (0.42) | EPHX1PBKGAAKMT2ADRD2 | |
| SCHEMBL26043679 | 0.83 | EPHX1 (0.62) | EPHX1CXCR4GAAKMT2AHDAC4 | |
| SCHEMBL851615 | 0.83 | TDP1 (0.56) | EPHX1CXCR4GAAKMT2ADRD2 | |
| SCHEMBL60318 | 0.83 | EPHX1 (0.56) | EPHX1GAAKMT2ADRD2ACACB | |
| SCHEMBL5122815 | 0.83 | PBK (0.47) | EPHX1PBKKMT2ADRD2ACACB | |
| SCHEMBL5113769 | 0.82 | EPHX1 (0.73) | EPHX1CXCR4GAAKMT2AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890703-B1 | PYRIMIDINE COMPOUNDS AS CHEMOKINE RECEPTORS INHIBITORS | TAIGEN BIOTECHNOLOGY CO LTD (TW) | 2016-05-11 | — | — | EP | disclosed |