Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.50 |
| ▸ | CCR5 | P51681 | 14/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3323605 | 0.86 | CCR2 (0.49) | CCR2CCR5 | |
| SCHEMBL13361852 | 0.84 | CCR2 (0.69) | CCR2CCR5 | |
| SCHEMBL3326103 | 0.84 | CCR2 (0.69) | CCR2CCR5 | |
| SCHEMBL18901672 | 0.84 | CCR2 (0.69) | CCR2CCR5 | |
| Hydrochloric Acid SCHEMBL4151284 | 0.83 | CCR2 (0.68) | CCR2CCR5 | |
| SCHEMBL13361844 | 0.81 | CCR2 (0.45) | CCR2CCR5 | |
| Trifluoroacetic Acid SCHEMBL3327336 | 0.81 | CCR2 (0.65) | CCR2CCR5 | |
| SCHEMBL4296524 | 0.73 | CCR2 (0.61) | CCR2CCR5 | |
| SCHEMBL13334991 | 0.73 | CCR2 (0.61) | CCR2CCR5 | |
| SCHEMBL3326350 | 0.73 | CCR2 (0.61) | CCR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618970-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |