Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.69 |
| ▸ | CCR5 | P51681 | 14/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3326103 | 1.00 | CCR2 (0.69) | CCR2CCR5POLBTSHRHTT | |
| SCHEMBL13361852 | 1.00 | CCR2 (0.69) | CCR2CCR5POLBTSHRHTT | |
| Hydrochloric Acid SCHEMBL4151284 | 0.99 | CCR2 (0.68) | CCR2CCR5POLBTSHRHTT | |
| Trifluoroacetic Acid SCHEMBL3327336 | 0.96 | CCR2 (0.65) | CCR2CCR5POLBTSHRHTT | |
| SCHEMBL13361867 | 0.85 | CCR2 (0.61) | CCR2CCR5 | |
| SCHEMBL3326350 | 0.85 | CCR2 (0.61) | CCR2CCR5 | |
| SCHEMBL4296524 | 0.85 | CCR2 (0.61) | CCR2CCR5 | |
| SCHEMBL3331213 | 0.85 | CCR2 (0.75) | CCR2CCR5 | |
| SCHEMBL13627644 | 0.84 | CCR2 (0.50) | CCR2CCR5 | |
| Trifluoroacetic Acid SCHEMBL3323605 | 0.82 | CCR2 (0.49) | CCR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |