Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.46 |
| ▸ | CTSS | P25774 | 6/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3012283 | 0.85 | CTSS (0.50) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL7351243 | 0.85 | CYP1A2 (0.46) | CTSKCTSSSCN9ACTSLCTSB | |
| SCHEMBL607556 | 0.85 | CYP1A2 (0.46) | CTSKCTSSSCN9ACTSLCTSB | |
| SCHEMBL30483892 | 0.84 | BMP1 (0.48) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL13159728 | 0.84 | CTSS (0.46) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL21737877 | 0.84 | CTSS (0.47) | CTSKCTSSSCN9ACTSLCTSB | |
| SCHEMBL12637878 | 0.84 | CTSS (0.47) | CTSKCTSSSCN9ACTSLCTSB | |
| SCHEMBL6566148 | 0.83 | CYP1A2 (0.48) | CTSKCTSSSCN9ACTSLCTSB | |
| SCHEMBL8029270 | 0.83 | CYP1A2 (0.44) | CTSKCTSSSCN9ACTSLCTSB | |
| SCHEMBL607848 | 0.83 | APP (0.49) | CTSKCTSSCTSLCTSBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |