Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.38 |
| ▸ | CCR1 | P32246 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627812 | 0.91 | CCR2 (0.42) | CCR2CCR1CCR5KCNH2 | |
| SCHEMBL13627585 | 0.89 | CCR2 (0.47) | CCR2CCR5OPRM1OPRK1OPRL1 | |
| SCHEMBL13627651 | 0.87 | CCR2 (0.39) | CCR2CCR5KCNH2 | |
| SCHEMBL13627581 | 0.81 | NAMPT (0.39) | CCR1ALDH1A1KCNH2 | |
| SCHEMBL13627813 | 0.75 | CCR2 (0.36) | CCR2CCR1CCR5KCNH2 | |
| SCHEMBL13627810 | 0.74 | CCR1 (0.46) | CCR1 | |
| SCHEMBL13741551 | 0.73 | CCR2 (0.64) | CCR2CCR1CCR5KCNH2 | |
| SCHEMBL4141218 | 0.73 | CCR2 (0.64) | CCR2CCR1CCR5KCNH2 | |
| SCHEMBL6015055 | 0.73 | CCR2 (0.64) | CCR2CCR1CCR5KCNH2 | |
| SCHEMBL13628365 | 0.73 | CCR1 (0.47) | CCR1OPRM1OPRK1OPRL1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618970-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |