Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.39 |
| ▸ | CCR5 | P51681 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627812 | 0.87 | CCR2 (0.42) | CCR2CCR5KCNH2 | |
| SCHEMBL13627811 | 0.87 | CCR2 (0.38) | CCR2CCR5KCNH2 | |
| SCHEMBL13627585 | 0.85 | CCR2 (0.47) | CCR2CCR5KCNH2 | |
| SCHEMBL13627813 | 0.81 | CCR2 (0.36) | CCR2CCR5KCNH2 | |
| SCHEMBL13628658 | 0.77 | KMT2A (0.38) | — | |
| SCHEMBL13628368 | 0.76 | DPP7 (0.36) | — | |
| SCHEMBL4146556 | 0.76 | CCR2 (0.66) | CCR2CCR5KCNH2 | |
| SCHEMBL13627581 | 0.76 | NAMPT (0.39) | KCNH2 | |
| SCHEMBL13627815 | 0.74 | CCR2 (0.48) | CCR2CCR5KCNH2 | |
| SCHEMBL13627656 | 0.72 | CCR2 (0.44) | CCR2CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618970-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |