⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835683 | 1.00 | ALDH1A1 (0.39) | — | |
| SCHEMBL29460954 | 1.00 | — | — | |
| SCHEMBL217939 | 0.82 | ALDH1A1 (0.38) | — | |
| SCHEMBL29350921 | 0.82 | ALDH1A1 (0.38) | — | |
| SCHEMBL5007782 | 0.76 | — | — | |
| SCHEMBL21611502 | 0.76 | — | — | |
| Pyrazine SCHEMBL27517504 | 0.74 | ALDH1A1 (0.43) | — | |
| SCHEMBL7939455 | 0.72 | — | — | |
| SCHEMBL14983692 | 0.72 | — | — | |
| SCHEMBL103808 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 885 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025129105-A1 | COMPOSITION AND METHOD FOR DETECTION OF BIOMOLECULES VIA AROMATIC LABELING USING HETEROCYCLIC COMPOUNDS | Life Technologies Corporation (US) | 2025-06-19 | — | — | WO | claimed |
| CN-116903634-A | Preparation method of 6-phenylthieno [2,3-b ] pyrazine | 上海美迪西生物医药股份有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-109182286-B | Improved cyano reductase and application thereof in synthesis of 3-chloropyrazine-2 methylamine | 泰州学院 | 2021-07-30 | — | — | CN | claimed |
| CN-110256409-B | Thermal activity delayed fluorescence organic compound with 2-cyanopyrazine as receptor and preparation and application thereof | 浙江虹舞科技有限公司 | 2021-01-15 | — | — | CN | claimed |
| CN-111377929-A | Preparation method of acarabtinib (acarabutinib) for treating leukemia | 南京艾德凯腾生物医药有限责任公司 | 2020-07-07 | — | — | CN | claimed |
| CN-111377928-A | Method for preparing acarabretinib | 南京艾德凯腾生物医药有限责任公司 | 2020-07-07 | — | — | CN | claimed |
| CN-110256409-A | It is a kind of using 2 cyano pyrazine as the thermal activities delayed fluorescence organic compound of receptor and its preparation and application | 浙江虹舞科技有限公司 | 2019-09-20 | — | — | CN | claimed |
| CN-109182286-A | Improved cyano reductase and application thereof in synthesis of 3-chloropyrazine-2 methylamine | 泰州学院 | 2019-01-11 | — | — | CN | claimed |
| CN-108164000-A | Glass plate of fixed ammonia oxidizing bacteria and preparation method thereof | 光合强化（北京）生物科技有限公司 | 2018-06-15 | — | — | CN | claimed |
| CN-102268014-B | Condensed heteroaryl derivative and its preparation method and use | ALLIST PHARMACEUTICALS INC | 2015-06-03 | — | — | CN | claimed |
| CN-102639535-B | Fused heteroaryl compounds, their preparation and use | SHANGHAI ALLIST PHARMACEUTICALS INC | 2014-11-12 | — | — | CN | claimed |
| CN-102675230-A | Preparation method of 3-amino-2-cyanogroup-6-bromide pyrazine | CGENE TECH SUZHOU CHINA CO LTD | 2012-09-19 | — | — | CN | claimed |
| CN-102639535-A | Fused heteroaryl compounds, their preparation and use | SHANGHAI ALLIST PHARMACEUTICALS INC | 2012-08-15 | — | — | CN | claimed |
| CN-102268014-A | Condensed heteroaryl derivative and its preparation method and use | — | 2011-12-07 | — | — | CN | claimed |
| CN-102020657-A | Condensed heteroaryl derivative, and preparation method and application thereof | ALLIST PHARMACEUTICALS INC | 2011-04-20 | — | — | CN | claimed |
| US-12545682-B2 | Heterocyclic derivatives as P2X7 receptor antagonists | BREYE THERAPEUTICS APS (DK) | 2026-02-10 | — | — | US | disclosed |
| US-20260001885-A1 | 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS | MERCK SHARP & DOHME (NL) | 2026-01-01 | — | — | US | disclosed |
| US-4293552-A | Novel 1-(mono-o-substituted benzoyl)-3-(substituted pyrazinyl) ureas | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |