SCHEMBL217939

SCHEMBL217939

N#Cc1nccnc1C#N

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
LMNA P02545 2/20 0.38
PKM P14618 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
PAX8 Q06710 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KDM4E B2RXH2 2/20 0.34
POLB P06746 1/20 0.34
CYP11B1 P15538 1/20 0.34
PLCG1 P19174 1/20 0.33
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PIK3CD O00329 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30
ERBB2 P04626 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350921 1.00 ALDH1A1 (0.38) ALDH1A1MAPTLMNAPKMMAPK1
SCHEMBL136280 0.82
SCHEMBL7939455 0.82
SCHEMBL29460954 0.82
SCHEMBL16116196 0.82 ALDH1A1 (0.32) ALDH1A1MAPTLMNAPKMMAPK1
Pyrazine SCHEMBL8046266 0.80 ALDH1A1 (0.41) ALDH1A1MAPTLMNAPKMMAPK1
SCHEMBL2961830 0.80
SCHEMBL2683771 0.80
SCHEMBL620327 0.80
SCHEMBL14626138 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3305 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119331480-B Coating layer, secondary battery and electronic device 宁德新能源科技有限公司 2025-05-06 CN claimed
CN-119331480-A Coating layer, secondary battery and electronic device 宁德新能源科技有限公司 2025-01-21 CN claimed
CN-119009136-A Pyrazinyl eutectic electrolyte with wide electrochemical stability window, and preparation method and application thereof 中国科学院长春应用化学研究所 2024-11-22 CN claimed
CN-118183677-A Method for preparing lithium pre-doped amine coordination ferromanganese phosphate precursor from lithium ferromanganese phosphate 湖南邦普循环科技有限公司 2024-06-14 CN claimed
CN-118126376-A Antistatic PVC film and production process thereof 广州市楠芳塑料有限公司 2024-06-04 CN claimed
CN-118063794-A Preparation method of lignin containing primary amine groups 新疆农业大学 2024-05-24 CN claimed
CN-117924028-A Process for preparing 1, 4-butenediol from 1, 4-butynediol 中国石油化工股份有限公司 2024-04-26 CN claimed
CN-117884156-A Application of monoatomic ruthenium-based catalyst in preparation of propylene by propane dehydrogenation 中国科学院大连化学物理研究所 2024-04-16 CN claimed
CN-117736537-A Preparation method of epoxy resin-glass fiber composite insulating material of dry type air-core reactor 国网黑龙江省电力有限公司电力科学研究院 2024-03-22 CN claimed
CN-117604681-A SnFe 3 N@ carbon fiber composite material and preparation method and application thereof 西安建筑科技大学 2024-02-27 CN claimed
CN-1081742-A Piston and piston ring rare earth surface treatment technology LI JIFU (CN) 1994-02-09 CN claimed
EP-0308895-B1 DICYANOPYRAZINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND FUNGICIDE HODOGAYA CHEMICAL CO., LTD. (JP) 1993-06-16 EP claimed
US-5093335-A Agricultural and horticultural HODOGAYA CHEMICAL COMPANY, LTD. (JP) 1992-03-03 US claimed
EP-0308895-A1 Dicyanopyrazine compounds, process for their preparation and fungicide HODOGAYA CHEMICAL CO., LTD. (JP) 1989-03-29 EP claimed
CN-86107577-A Make the method and the equipment thereof of prepreg for printed circuit board and metal composite basis material 1987-04-29 CN claimed
EP-0088047-B1 N-CYANOCARBOXYLIC ACID AMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1986-03-12 EP claimed
CN-85100892-A Paper ion exchange membrane and preparation method thereof and application thereof in electrodialysis water purification treatment 1986-01-10 CN claimed
US-4460403-A 2,3-Dicyano 6 phenyl pyrazine herbicides KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) 1984-07-17 US claimed
US-4434017-A GAS-BUBBLE-SENSITIZED MELT OF OXIDIZER SALT, FUEL, SURFACTANT, THICKENERS ICI AUSTRALIA LIMITED (AU) 1984-02-28 US claimed
US-4259489-A PREEMERGENCE AND POSTEMERGENCE HERBICIDES KYOWA GAS CHEMICAL INDUSTRY CO. LTD. (JP) 1981-03-31 US claimed