Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | NT5E | P21589 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.52 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.52 |
| ▸ | RORC | P51449 | 6/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441761 | 0.90 | GPBAR1 (0.53) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL13637669 | 0.90 | GPBAR1 (0.53) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL13628262 | 0.88 | RORC (0.67) | GPBAR1LMNANT5EEGLN2EGLN1 | |
| SCHEMBL4445711 | 0.88 | RORC (0.67) | GPBAR1LMNANT5EEGLN2EGLN1 | |
| SCHEMBL13628400 | 0.86 | RORC (0.63) | GPBAR1LMNANT5EEGLN2EGLN1 | |
| SCHEMBL13628261 | 0.85 | GPBAR1 (0.51) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL4444101 | 0.85 | GPBAR1 (0.51) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL13637791 | 0.84 | GPBAR1 (0.58) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL13628477 | 0.84 | GPBAR1 (0.58) | GPBAR1LMNANT5ESMN1; SMN2EGLN2 | |
| SCHEMBL13637691 | 0.84 | TRPV1 (0.64) | GPBAR1LMNANT5EEGLN2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275583-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INCORPORATED (US) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275583-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MAVS, ZC3HAV1, EIF2AK2 | GPBAR1 3262/4885LMNA 2620/4885NT5E 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.