Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.47 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628810 | 0.79 | HDAC8 (0.61) | HDAC8NNMTKCNH2CA12CA2 | |
| SCHEMBL11777860 | 0.79 | APP (0.52) | KCNH2PDE2ACA12CA2CA9 | |
| Hydrochloric Acid SCHEMBL11706833 | 0.77 | MAPT (0.50) | KCNH2PDE2ACA12CA2CA9 | |
| Iodide SCHEMBL3260441 | 0.77 | HDAC8 (0.59) | HDAC8NNMTKCNH2CA12CA2 | |
| SCHEMBL24161328 | 0.66 | ALDH1A1 (0.41) | HDAC8PDE2ARARBRARGMAPT | |
| SCHEMBL8987968 | 0.65 | HDAC8 (1.00) | HDAC8NNMTMAPTUSP2 | |
| SCHEMBL8731836 | 0.65 | — | — | |
| SCHEMBL7702350 | 0.65 | — | — | |
| SCHEMBL1706121 | 0.65 | PDE2A (0.62) | KCNH2PDE2AMAPTAKT1AKT2 | |
| Iodide SCHEMBL8404077 | 0.64 | HDAC8 (0.96) | HDAC8NNMTMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611546-B2 | Composition comprising at least one substituted acetylenic carbocyanin derivative, process for treating keratin fibres using it, and device therefor | L'OREAL S.A. (FR) | 2009-11-03 | — | — | US | disclosed |