Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21711289 | 0.79 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21711302 | 0.79 | LMNA (0.36) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6304343 | 0.79 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21711299 | 0.78 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL22601410 | 0.77 | ALDH1A1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL13313571 | 0.77 | IKBKB (0.40) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21675343 | 0.76 | ALDH1A1 (0.34) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL22847418 | 0.76 | ALDH1A1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL11955241 | 0.73 | MEN1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL19945191 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310787-B9 | TAGGABLE HETEROAROMATIC DRUGS AND CONJUGATES THEREOF | UNIV RAMOT (IL) | 2020-07-01 | — | — | EP | disclosed |
| WO-2020033880-A1 | IMIDAZOTETRAZINE COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-02-13 | — | — | WO | disclosed |
| EP-3290035-A1 | PROCASPASE COMBINATION THERAPY FOR TREATING CANCER | The Board of Trustees of the University of Illinois (US) | 2018-03-07 | — | — | EP | disclosed |
| US-7612202-B2 | Process for preparing temozolomide | CHEMAGIS, LTD. (IL) | 2009-11-03 | — | — | US | disclosed |