Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13629403 | 0.89 | CES1 (0.58) | MEN1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL13629418 | 0.88 | PKM (0.61) | ALDH1A1LMNAMAPTPGRPKM | |
| SCHEMBL13629553 | 0.84 | PKM (0.56) | ALDH1A1LMNAMAPTCYP3A4CYP2D6 | |
| SCHEMBL29561406 | 0.81 | MEN1 (0.59) | MEN1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL13629411 | 0.80 | PPARG (0.55) | MEN1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL13629296 | 0.80 | ALDH1A1 (0.57) | MEN1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL13629427 | 0.79 | ALDH1A1 (0.54) | MEN1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL13615171 | 0.79 | MEN1 (0.48) | MEN1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL13629417 | 0.78 | KMT2A (0.52) | MEN1LMNAKMT2AMAPTNPSR1 | |
| SCHEMBL13853000 | 0.78 | KMT2A (0.55) | MEN1ALDH1A1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275593-A1 | 3 Substituted N-(aryl- or heteroaryl)-pyrazolo[1,5-a]pyrimidines as Kinase Inhibitors | NOVARTIS AG | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275593-A1 | 3 Substituted N-(aryl- or heteroaryl)-pyrazolo[1,5-a]pyrimidines as Kinase Inhibitors | TIE1, TEK, MATK | MEN1 1920/4885ALDH1A1 2121/4885LMNA 2608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.