Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.48 |
| ▸ | BRPF1 | P55201 | 5/20 | 0.46 |
| ▸ | BRD1 | O95696 | 2/20 | 0.46 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CCNH | P51946 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13629466 | 0.87 | BRPF1 (0.46) | SLC22A12BRPF1BRD1BRPF3PIK3C3 | |
| SCHEMBL13615230 | 0.83 | SLC22A12 (0.48) | SLC22A12BRPF1BRD1BRPF3TRIM24 | |
| SCHEMBL13629339 | 0.81 | BRD4 (0.51) | BRD4LMNASMN1; SMN2SGK1CDK1 | |
| SCHEMBL13629320 | 0.80 | SLC22A12 (0.54) | SLC22A12BRD4LMNA | |
| SCHEMBL13629322 | 0.79 | CDK1 (0.51) | PIK3C3LMNASGK1CDK1CCNB1 | |
| SCHEMBL16325840 | 0.78 | SLC22A12 (0.47) | SLC22A12BRPF1BRD1BRPF3BRD4 | |
| SCHEMBL94461 | 0.77 | SLC22A12 (0.48) | SLC22A12PIK3C3LMNAPPARG | |
| SCHEMBL13629329 | 0.76 | ALDH1A1 (0.65) | LMNASMN1; SMN2CDK1CCNB1CCNA2 | |
| SCHEMBL13615237 | 0.75 | SLC22A12 (0.47) | SLC22A12BRPF1BRD1BRPF3TRPV4 | |
| SCHEMBL13629401 | 0.75 | ALDH1A1 (0.65) | SLC22A12BRD4LMNACDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275593-A1 | 3 Substituted N-(aryl- or heteroaryl)-pyrazolo[1,5-a]pyrimidines as Kinase Inhibitors | NOVARTIS AG | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275593-A1 | 3 Substituted N-(aryl- or heteroaryl)-pyrazolo[1,5-a]pyrimidines as Kinase Inhibitors | TIE1, TEK, MATK | SLC22A12 4627/4885BRPF1 3189/4885BRD1 1062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.