SCHEMBL136295

SCHEMBL136295

CN(C)c1ccc(C=C2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.59
APP P05067 7/20 0.59
SNCA P37840 7/20 0.59
ALDH1A1 P00352 5/20 0.59
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
PDGFRB P09619 2/20 0.59
MAPK1 P28482 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
HPGD P15428 2/20 0.59
PKM P14618 2/20 0.59
NPC1 O15118 1/20 0.59
GMNN O75496 1/20 0.59
LMNA P02545 1/20 0.59
MTOR P42345 1/20 0.59
RAB9A P51151 1/20 0.59
BLM P54132 1/20 0.59
PMP22 Q01453 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9803755 0.85 MAPT (0.54) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL4165013 0.84 MAOB (0.56) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL13508401 0.83 CYP19A1 (0.55) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL29609334 0.83 MIF (0.70) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL1454792 0.83 MIF (0.70) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL27479399 0.82 MAPT (0.48) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL3569139 0.80 MAPT (0.76) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL13343862 0.80 MAPT (0.76) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL13343863 0.80 MAPT (0.76) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL14570730 0.80 CYP19A1 (0.52) MAPTAPPSNCAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6645686-B1 Electrophotographic imaging members XEROX CORPORATION 2003-11-11 US claimed
US-4596754-A Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin RICOH COMPANY, LTD. (JP) 1986-06-24 US claimed
EP-2290449-B1 Flexible imaging member belts XEROX CORP (US) 2017-05-24 EP disclosed
US-9482969-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2016-11-01 US disclosed
US-20160154327-A1 CHARGE TRANSPORT LAYER FOR IMAGING DEVICE XEROX CORPORATION 2016-06-02 US disclosed
CN-103242167-B Amine compound, photoelectric conductor for electronic photography, image forming method, image forming apparatus and handle box RICOH CO., LTD. (JP) 2016-02-24 CN disclosed
US-9235146-B2 Photoconductor RICOH COMPANY, LTD. (JP) 2016-01-12 US disclosed
US-9091949-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-07-28 US disclosed
US-9075327-B2 Imaging members and methods for making the same XEROX CORPORATION (US) 2015-07-07 US disclosed
US-20150177629-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION 2015-06-25 US disclosed
US-9046798-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-06-02 US disclosed
US-4619878-A Tetrazonium salt compound, disazo compound, method for preparing the same, and photosensitive material containing said disazo compound for use in electrophotography RICOH CO., LTD. (JP) 1986-10-28 US disclosed
US-4596754-A Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin RICOH COMPANY, LTD. (JP) 1986-06-24 US disclosed
US-4582771-A Disazo compound, method for preparing the same, and electrophotographic element containing the same for use in electrophotography RICOH CO., LTD. (JP) 1986-04-15 US disclosed
US-4565759-A PHOTOCONDUCTIVE LAYER ON ELECTROCONDUCTIVE SUPPORT RICOH CO., LTD. (JP) 1986-01-21 US disclosed
US-4540643-A Tetrazonium salt compounds, novel disazo compounds, method for the production thereof and disazo compound-containing electrophotographic elements RICOH CO., LTD. (JP) 1985-09-10 US disclosed
US-4536458-A Migration imaging system XEROX CORPORATION (US) 1985-08-20 US disclosed
US-4536457-A Migration imaging process XEROX CORPORATION (US) 1985-08-20 US disclosed
EP-0149328-A1 Migration imaging member and method XEROX CORPORATION (US) 1985-07-24 EP disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed