Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | APP | P05067 | 7/20 | 0.54 |
| ▸ | SNCA | P37840 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MTOR | P42345 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | THPO | P40225 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508381 | 0.86 | HTR6 (0.46) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL136295 | 0.85 | MAPT (0.59) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL31614556 | 0.85 | HTR6 (0.63) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL29448173 | 0.85 | HTR6 (0.63) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL1454605 | 0.85 | HTR6 (0.63) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL1454609 | 0.85 | HTR6 (0.63) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL2605592 | 0.83 | HTR6 (0.41) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL2605593 | 0.83 | HTR6 (0.44) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL9804011 | 0.82 | ALDH1A1 (0.50) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL9803880 | 0.81 | HTR6 (0.40) | MAPTAPPSNCAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5024912-A | 5H-dibenzo(A,D) cycloheptanylidene derivative and 5H-dibenzo (A,D) cycloheptenylidene derivative, and electrophotographic photosensitive member using the same | CANON KABUSHIKI KAISHA (JP) | 1991-06-18 | — | — | US | disclosed |