Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.32 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.32 |
| ▸ | TEAD2 | Q15562 | 2/20 | 0.32 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156196 | 0.81 | PARP1 (0.33) | PARP1TEAD1TEAD4TEAD2TEAD3 | |
| SCHEMBL13629594 | 0.76 | MAPT (0.38) | PTGS1PTGS2PARP1CYP2A6 | |
| SCHEMBL14189080 | 0.72 | PARP1 (0.54) | PTGS1PTGS2PARP1CYP2A6 | |
| SCHEMBL8011587 | 0.71 | PARP1 (0.37) | PTGS1PTGS2PARP1CYP2A6 | |
| SCHEMBL7490063 | 0.69 | PTGES (0.41) | PARP1 | |
| SCHEMBL15189277 | 0.68 | FFAR4 (0.42) | PTGS1PTGS2FFAR4HRH4GRIN2B | |
| SCHEMBL7484709 | 0.68 | PARP1 (0.39) | PTGS1PTGS2PARP1CYP2A6 | |
| SCHEMBL6342164 | 0.68 | MAPT (0.36) | PTGS1PTGS2PARP1CYP2A6 | |
| SCHEMBL8466298 | 0.68 | PARP1 (0.39) | PTGS1PTGS2PARP1CYP2A6 | |
| SCHEMBL5542428 | 0.68 | PARP1 (0.39) | PTGS1PTGS2PARP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |