Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13629596 | 0.83 | TACR1 (0.46) | TACR1NOTUMALDH1A1HSP90AA1MAPT | |
| SCHEMBL13629600 | 0.82 | LMNA (0.45) | TACR1NOTUMALDH1A1HSP90AA1MAPT | |
| SCHEMBL5815553 | 0.82 | TACR1 (0.44) | TACR1 | |
| SCHEMBL7521070 | 0.82 | TACR1 (0.51) | TACR1 | |
| SCHEMBL6580528 | 0.78 | TACR1 (0.41) | TACR1 | |
| SCHEMBL6541068 | 0.76 | NOTUM (0.46) | TACR1NOTUMALDH1A1HSP90AA1MAPT | |
| SCHEMBL13630147 | 0.76 | TACR1 (0.46) | TACR1NOTUMALDH1A1HSP90AA1MAPT | |
| SCHEMBL7517331 | 0.74 | TACR1 (0.54) | TACR1 | |
| SCHEMBL8517947 | 0.72 | NOTUM (0.45) | TACR1NOTUMALDH1A1HSP90AA1MAPT | |
| SCHEMBL8176205 | 0.72 | TACR1 (0.48) | TACR1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |